centrosome造句_centrosome例句_centrosome用法_V5词典

1. IntroductionThe centrosome is the major microtubule organizing center ( MTOC) of mammalian cells.: 中心体是哺乳类细胞主要的微管组织中心。

2. Centrosome is a kind of tiny cellular organ, and it plays an important role in the maintenance of cellular polarity and chromosomal segregation during mitosis.: 中心体这一微小的细胞器，在有丝分裂中对维持细胞的极性及染色体分离具有重要的调节作用。

3. Aurora kinases play important roles in many events during cell mitosis, such as centrosome maturation and separation, spindle assembly and maintenance, chromosome segregation, cytokinesis and so on.: 在细胞有丝分裂中，极光激酶参与了诸如中心体成熟分离、纺锤体组装和维持、染色体分离以及胞质分裂等多个事件。

4. The study of regulation mechanism about centrosome replication can play an important role in early diagnosis and treatment of tumor.: 研究中心体复制调控机制，对肿瘤的早期诊断和治疗有重要的作用。

5. Accordingly, the researchers have proved that these checkpoint kinases also exist alongside the centrosome and perform their function there.: 由此，科学家们证实这些检测点激酶同样存在于细胞中心体附近，并发挥着他们的作用。

6. Relatively little is known about the inner workings of centrosomes even after a century of study, and the investigators suggest their discovery could explain centrosome evolution and function.: 中心体的发现和研究已经超过一世纪，但我们对其内部运作机制仍所知有限，科学家认为这项发现将有助于解释中心体的演化和功能。

7. The cell cycle arrest is transient, and GSCs appear to re-enter the cell cycle on correction of centrosome orientation.: 这种停滞是暂时的，中心体取向被纠正后，细胞会重新进入细胞周期。

8. The centrosome, the major microtubule organizing center regulates cell division through forming bipolar mitotic spindles and plays an essential role in the maintenance of chromosomal stability.: 中心体作为细胞的主要微管组织中心，在细胞周期过程中建立两极纺锤体，调节细胞有丝分裂，从而对维持染色体的稳定起着重要的作用。

9. The centrosome probably plays an important role in the reorganization of the cell that occurs during differentiation.: 在细胞分化的过程中中心体扮演着重要的角色。

10. The entire cell aster with the exception of the centrosome .: 属于或与细胞的中心体有关。

11. Overexpression of STK15 induces increased numbers of centrosome, aneuploidy, and transformation of the cells.: STK15过表达诱导中心体数目增多，异倍体形成和细胞转化。

12. Centrosome duplication is a key requirement for bipolar spindle formation and correct segregation of chromosomes during cell division.: 中心体的正常复制对于细胞分裂时双极纺锤体的形成、染色体的正确分离是至关重要的。

13. With development of the research, the complicated function of centrosome and its im-portance have gradually been realized.: 随着研究的进展，人们不断认识到中心体的复杂功能及其重要性。

14. The roles of centrosome abnormality in the origination and development of cancers, especially in bladder transitional cell carcinoma are reviewed.: 现就有关中心体异常在恶性肿瘤特别是膀胱移行细胞癌发生进展中的作用作一综述。

15. They form a connection between the starting point in the chromosomes, the kinetochore, and the centrosome .: 他们将染色体、着丝粒和中心体的起点连接起来。

16. Centrosome A structure found in all eukaryotic cells, except fungi, that forms the SPINDLE during cell division.: 在除真菌以外的所有真核细胞中存在一种结构，在细胞分裂时可以形成纺锤体。

17. The coordination of the centrosome cycle and cell cycle ensures an accurate distribution of genetic material.: 中心体周期和细胞周期相互配合以保证遗传物质的精确分配。

18. Therefore, tumor cell gene instability and centrosome abnormalities are closely related to.: 因此，肿瘤细胞基因不稳定与中心体异常密切相关。

19. Perturbation of the spatiotemporal dynamics of centrosome splitting can lead to genomic instability during cell division.: 扰乱中心体分裂的时空动态性会导致细胞分离中基因组的不稳定性。

20. Malfunctions in centrosome cohesion and separation, in fact, have been seen in many solid tumors.: 事实上，在很多实体瘤中都发现过中心体连接和分离的机能失常。

21. Many centrosome-related proteins and kinases have been found to regulate different steps of centrosome duplication.: 现已发现了许多中心体蛋白及与中心体复制相关的蛋白激酶，调控着中心体复制的各个步骤。

22. More and more importance is attached to the correlation between centrosome abnormity and tumorigenesis, It refers to multiple genes abnormity, mainly separated into oncogene and tumor suppressor gene.: 中心体异常与肿瘤发生的相关性已越来越受到人们的重视。

23. Collectively, these results demonstrate that negative regulation of CPAP self-interaction by mitotic phosphorylation is required for accurate centrosome cohesion and splitting during the cell cycle.: 综上所述，有丝分裂期CPAP的自身相互作用被磷酸化作用负调控，这对于中心体连接和分裂在细胞周期中的精确调控有重要作用。

24. Centrosome amplification could be served as an alternative diagnostic indicator of dysplasia and cervical squamous cell cancer.: 中心体异常扩增可作为一个客观的细胞形态学异常的指标，辅助宫颈癌前病变及宫颈鳞癌诊断。

25. So gene instability of tumor cells may be closely correlated with centrosome abnormality, which is a common feature of malignant tumor cells.: 因此肿瘤细胞基因不稳定可能与中心体异常密切相关。中心体异常是恶性肿瘤细胞的普遍特征。

26. Moreover, this self-interaction is required for maintaining centrosome cohesion and preventing the centrosome from splitting before G2/M phase.: 而且，这种自身相互作用参与了中心体连接的维持并抑制了G2/M期之前中心体的分裂。

27. In G2/M phase, centrosome cohesion dissipates and centrosome splitting happened and two centrosomes separate into two functional units to form the bipolar spindle.: 在G2/M期，中心体连接消散，发生中心体分裂，两个中心体分离成为两个独立功能的个体形成两极纺锤体。

28. In G2/M phase, centrosome cohesion dissipates and centrosome splitting happened and two centrosomes separate into two functional units to form the bipolar spindle.: 在G2/M期，中心体连接消散，发生中心体分裂，两个中心体分离成为两个独立功能的个体形成两极纺锤体。

29. of or relating to a centrosome.: 属于或与细胞的中心体有关。

30. The entire cell aster with the exception of the centrosome.: 空心体，吸收体除中心体外的整个星体

31. a star-shaped structure formed in the cytoplasm of a cell and having raylike fibers that surround the centrosome during mitosis.: 在细胞浆内形成的星状结构,在有丝分裂期间有棱形纤维环绕中心体。

32. The mass of cytoplasm surrounding the centriole in a centrosome.: 中心球在中心体内中心粒周围的大量细胞质

33. proximal centrosome: 近侧中心体

34. IntroductionThe centrosome is the major microtubule organizing center ( MTOC) of mammalian cells.: 中心体是哺乳类细胞主要的微管组织中心。

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